Originality and Trust
Neuramis orders are prepared around sealed packaging, visible lot details, expiry review, and consistent product presentation before export.
Neuramis Wholesale Portfolio for B2B Clinic Supply
Neuramis is a Korean HA dermal filler portfolio from Medytox, covering five variants from superficial hydration to deep volumizing. Clinics ordering Neuramis wholesale get a single procurement path for fine lines, folds, lip work, and structural contouring without managing multiple filler supply chains.
Table of Contents
- Neuramis Portfolio Supply for Clinics and Distributors
- Neuramis Export Timeline
- Neuramis Quick Product Specs
- Neuramis Variants & Comparison Matrix
- Neuramis Evidence & Documentation
- What is Neuramis? Corporate Profile
- Neuramis Mechanism of Action & SHAPE Technology
- Neuramis Target Areas & Indications
- Neuramis Clinical Efficacy & Comparative Performance
- Neuramis Visible Improvements
- Neuramis Administration Protocol & Aftercare
- Neuramis Originality, Trust & Buyer Support
- Wholesale Dermal Fillers
- Frequently Asked Questions (FAQ)
Neuramis Portfolio Supply for Clinics and Distributors
Yaksu Medi works as a Korean supplier for clinics and distributors that need original Neuramis stock, clear communication, and reliable export handling. The goal is not only to quote boxes, but to help buyers build a repeatable wholesale supply rhythm.
What sets Neuramis wholesale procurement apart is its five-variant architecture. Rather than sourcing superficial, mid-dermal, and volumizing fillers from separate supply chains, your clinic can consolidate the HA filler spectrum into a single buying process. For buyers comparing dermal fillers wholesale options, Neuramis supports broad anatomical coverage with one coordinated shipment plan.
Reliable Neuramis Wholesale Pricing
We structure B2B pricing around quantity, variant mix, destination, and route so clinics can plan inventory with clear wholesale value.
Fast Carrier Handoff
Confirmed orders move quickly into packing and dispatch, with FedEx, EMS, air freight branch handoff, and larger cargo options discussed by destination.
Customer Satisfaction and Reorder Support
After delivery, we help buyers review usage speed, reorder timing, and future bulk order needs so clinic inventory stays predictable.
Key Export Destinations
United States, Canada, United Kingdom, Germany, Poland, France, Italy, Spain, Albania, United Arab Emirates (Dubai), Saudi Arabia, Qatar, Kuwait, Turkey, Brazil, Colombia, Argentina, Mexico, Thailand, Japan, Australia.
For clinics already familiar with Neuramis, we provide a direct restocking channel. For buyers planning a Neuramis bulk order for the first time, we help match variants, quantity, and route before quoting.
Neuramis Export Timeline for B2B Buyers
Neuramis procurement is handled as a quote-led B2B export workflow rather than a public cart checkout.
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Product Inquiry
The clinic or distributor asks for Neuramis availability, target variants, destination country, and estimated wholesale quantity.
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Supply Status Check
We confirm current stock, variant mix, expiry window, and export feasibility before the buyer finalizes the order.
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Order Creation
After the buyer confirms quantity and variant selection, the Neuramis order is created with destination details and B2B shipment requirements.
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Payment Confirmation
The customer completes payment, and the confirmed order moves into packing and dispatch preparation.
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Dispatch and Air Freight Handoff
The shipment is released through the agreed route: FedEx, EMS, air freight branch handoff, or container shipment for larger wholesale orders when suitable.
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Delivery and Reorder Planning
After delivery, we help the buyer plan the next Neuramis bulk order based on usage speed, remaining inventory, and variant demand.
Neuramis Quick Product Specs
Manufacturer Medytox Inc., South Korea
Product Type Monophasic hyaluronic acid dermal filler portfolio
Variants Light Lidocaine, Lidocaine, Deep, Deep Lidocaine, Volume Lidocaine
Technology SHAPE stabilization and purification enhancement
Residual BDDE Non-detectable by standard analysis, reported below 0.4 ppm
Storage Range 2°C to 25°C, protected from direct sunlight
Shelf Life 24 months from manufacturing date
Best-Fit Buyer Clinics and distributors planning multi-depth HA filler inventory
Neuramis Variants & Comparison Matrix
The Neuramis portfolio is segmented by rheology, particle calibration, injection depth, and lidocaine preference. This lets clinics compare the full range before building a wholesale order for fine lines, folds, lip work, and deeper contouring.
| Variant | Best for | Depth / Area | Needle | Lidocaine | Procurement note |
|---|---|---|---|---|---|
| Neuramis Light Lidocaine | Superficial rhytides and delicate hydration | Superficial dermis | 30G UTW | Yes, 0.3% | Useful for clinics that need lighter HA stock for fine texture work. |
| Neuramis Lidocaine | Moderate wrinkles and soft contouring | Middle dermis | 30G UTW | Yes, 0.3% | A versatile option for mixed Neuramis bulk orders. |
| Neuramis Deep | Severe folds and lidocaine-sensitive protocols | Deep dermis | 27G UTW | No | A lidocaine-free option for clinics that need anesthetic-sensitive pathways. |
| Neuramis Deep Lidocaine | Nasolabial folds, marionette lines, and lips | Deep dermis | 27G UTW | Yes, 0.3% | Frequently prioritized as the core high-demand Neuramis stock item. |
| Neuramis Volume Lidocaine | Deep contouring, cheek projection, chin, and jawline | Deep subcutaneous or supraperiosteal layer | 27G UTW | Yes, 0.3% | Adds deep structural coverage to a complete Neuramis portfolio order. |
Neuramis Light Lidocaine
Specs: Extra-small molecules, 0.3% lidocaine, 30G UTW needle
Clinics order Neuramis Light Lidocaine for superficial rhytides, periorbital hydration, and fine texture correction where a lighter HA gel is preferred.
Neuramis Lidocaine
Specs: Small molecules, 0.3% lidocaine, 30G UTW needle
Neuramis Lidocaine is often included in a Neuramis bulk order for moderate wrinkles and superficial-to-mid dermal contouring with integrated procedural comfort.
Neuramis Deep
Specs: Medium molecules, lidocaine-free, 27G UTW needle
For severe fold corrections, Neuramis Deep gives clinics a lidocaine-free medium-molecule option. Practices that order Neuramis Deep can support patients with amide-type anesthetic sensitivities.
Most Preferred Variant 
Neuramis Deep Lidocaine
Specs: Medium molecules, 0.3% lidocaine, 27G UTW needle
Neuramis Deep Lidocaine is the flagship variant for nasolabial folds, marionette lines, and lip volumization. Reliable Neuramis Deep Lidocaine stock helps clinics meet recurring patient demand with consistent handling.
Neuramis Volume Lidocaine
Specs: Large molecules, 0.3% lidocaine, 27G UTW needle
Neuramis Volume Lidocaine gives clinics the highest-viscosity option in the portfolio for deep contouring, cheek projection, and chin augmentation.
Neuramis Evidence & Documentation
Visible source documents make the Neuramis wholesale page easier to verify for clinic buyers and easier for search systems to understand.
Medytox Aesthetic Solutions
Corporate and product portfolio document covering Medytox aesthetic injectable positioning.
View Medytox PDFNeuramis Brochure
Clinical data, SHAPE technology overview, mechanical properties, and portfolio details.
View Neuramis BrochureWhat is Neuramis? Corporate Profile
Neuramis is a distinguished line of hyaluronic acid (HA) dermal fillers engineered by Medytox Inc., a premier South Korean biopharmaceutical leader established in 2000. Recognizing the demands of high-stakes medical aesthetics, practitioners rely on the clinical confidence delivered by the Neuramis wholesale portfolio.
Medytox secures its raw HA materials from Shiseido in Japan, which are registered in the US FDA Drug Master Files (DMF) and certified by the EDQM. This biopharmaceutical pedigree means that when clinics source Neuramis wholesale, they access a product with purity standards positioned above European Pharmacopoeia requirements. The internal management standard for residual protein is below 0.1%, helping minimize delayed hypersensitivity risk.
Neuramis Mechanism of Action & SHAPE Technology
The foundation of every reliable Neuramis wholesale distribution is its proprietary manufacturing process. Neuramis uses SHAPE technology, meaning Stabilized Hyaluronic Acid and Purification Enhancement, to deliver a cohesive monophasic HA gel.
The 2-Step Cross-Linking Process
SHAPE technology uses a patented two-step cross-linking process to create a stable three-dimensional HA structure. A lengthy natural dialysis process then minimizes unreacted Butanediol Diglycidyl Ether (BDDE) to levels frequently non-detectable by standard analytical equipment, reported below 0.4 ppm.
| Parameter | Industry Standard | Neuramis Internal Standard |
|---|---|---|
| Residual BDDE | Below 2.0 ppm | Non-detectable, below 0.4 ppm |
| Residual Protein | Max 0.1% to 0.3% | Below 0.1% |
| Endotoxin | Below 0.5 IU/mg | Below 0.04 IU/mg |
Monophasic Polydensified Integration
Unlike biphasic fillers that can form isolated pools compressing surrounding tissues, Neuramis is a monophasic gel. It exhibits strong cohesiveness, spreading within the reticular dermis to fill interstitial spaces between collagen and elastin fibrils.
- Higher viscosity: Resists gel displacement and helps maintain shape in dynamic areas.
- Outstanding cohesivity: High affinity between molecules supports homogeneous integration without fragmentation.
| Rheological Feature | Neuramis Monophasic Profile | Traditional Biphasic Fillers |
|---|---|---|
| Gel Structure | Homogeneous and monodensified | Particulate, suspended in non-cross-linked HA |
| Cohesivity | High resistance to water dispersal | Lower resistance and more prone to fragmentation |
| Tissue Integration | Diffuse spreading between collagen fibers | Often forms isolated pools that compress tissue |
| Injection Force | Lower, supported by UTW needles | Variable, typically requiring higher force |
Neuramis Target Areas & Indications by Variant
Because each Neuramis formulation has distinct rheological properties and particle sizes, application depths and target areas are categorized to support tissue integration and reduce migration risk.
Neuramis Light Lidocaine
Designed for the superficial dermis. Its extra-small particle size and low viscosity support ultra-fine corrections without causing the Tyndall effect or palpable lumps.
- Periorbital lines and delicate tear trough hydration.
- Fine perioral lines.
- Glabellar lines and subtle dermal hydration.
Neuramis Lidocaine
Targeted at the middle dermis. With small particles, this is a versatile option for moderate wrinkle correction and soft augmentation.
- Standard lip volumization and contouring.
- Moderate forehead lines.
- Early-stage marionette lines and mild nasolabial folds.
Neuramis Deep and Neuramis Deep Lidocaine
Formulated for the deep dermis. Medium-sized particles with high cohesivity support severe fold correction and dynamic facial movement.
- Severe nasolabial folds.
- Deep forehead wrinkles.
- Structural lip contouring where border definition is critical.
Neuramis Volume Lidocaine
Intended for the deep subcutaneous or supraperiosteal layers. It has the highest elastic modulus and largest particles in the portfolio.
- Cheek augmentation and malar projection.
- Chin contouring and elongation.
- Jawline definition and mandibular angle support.
Neuramis Clinical Efficacy & Comparative Performance
The decision to use Neuramis wholesale stock over other filler lines is supported by Phase III randomized clinical data and visible product documentation.
Superior NLF correction: In a double-blind trial against a leading biphasic competitor, Neuramis Deep Lidocaine achieved a higher Wrinkle Severity Rating Scale improvement of 1.64 +/- 0.74 at week 24, compared with 1.45 +/- 0.54 in the control group.
Long-term durability: A 104-week longitudinal comparison involving Neuramis Volume Lidocaine showed sustained responder performance in Asian populations, supporting long-term structural stability.
Lower inflammatory response: Histopathological evaluations in mini-pig models report lower inflammatory cell infiltration scores than traditional biphasic competitors.
Neuramis Visible Improvements (Before & After)
A consistent Neuramis wholesale inventory supports predictable treatment planning for clinics. The following visual examples show the type of improvements clinics evaluate when planning Neuramis Deep Lidocaine and lip-focused HA filler stock.
Neuramis Administration Protocol & Aftercare
Precise delivery mechanics are facilitated by Medytox Ultra Thin Wall needles, which increase the inner diameter while maintaining a 27G or 30G outer gauge. This minimizes extrusion force and hand fatigue during demanding clinic schedules.
Luer Lock Cap Removal Protocol
To avoid mechanical failure, clinics should follow the product-specific cap removal model.
- Counter-clockwise rotation: Used for models BN, BNT1, BO, BNY, and BM2.
- Snap and tilt: Used for models NN, NNT1, NO, NO2, VO2, NNY, NM2, VM2, NMT1, and VMT1.
- Direct pull: Used for model SO.
Post-Treatment Mandates
- 24 hours: Periodic cold compression to manage edema. No alcohol or oil-based makeup.
- 48 hours: Avoid strenuous physical activity, UV exposure, and extreme temperatures.
- 1 week: Avoid ancillary cosmetic interventions such as lasers, peels, and facial massage.
Neuramis Originality, Trust & Buyer Support
For wholesale buyers, product originality, reliable pricing, fast dispatch, and consistent after-order support matter as much as the product itself.
Original Neuramis Supply
Each order is prepared around factory-sealed presentation, visible lot details, and packaging consistency so buyers can evaluate product originality before dispatch.
Reliable Buyer Trust
We keep communication clear around stock, expiry window, order status, and shipment route so clinics can buy with confidence instead of guessing.
Reliable Neuramis Wholesale Pricing
Pricing is planned for professional buyers through volume, variant mix, and route requirements, helping clinics access strong B2B value at competitive Korean export rates.
Fast Handoff and Satisfaction
Confirmed orders move quickly into packing and carrier handoff, with follow-up support for delivery status, reorder planning, and long-term customer satisfaction.
Wholesale Dermal Fillers
Neuramis Wholesale FAQ
Wholesale & MOQ
How can clinics request Neuramis MOQ and B2B pricing?
MOQ and B2B pricing depend on destination country, variant mix, and total volume. Use the WhatsApp quote button to request pricing for a single Neuramis variant or a mixed Neuramis bulk order.
Can clinics order Neuramis Deep and Neuramis Deep Lidocaine together?
Yes. Clinics can order Neuramis Deep and Neuramis Deep Lidocaine together when they need both lidocaine-free and comfort-focused protocols. We can quote both variants within the same Neuramis wholesale request.
Shipping & Storage
How should Neuramis be stored after delivery?
Maintain inventory temperatures between 2°C and 25°C. Protect from direct sunlight. Do not freeze, heat, or apply external pressure to the pre-filled syringes.
Does Neuramis require cold-chain export?
Neuramis is less temperature-restricted than toxin products, but export still requires protected, temperature-aware handling. We prepare shipments around destination, transit time, and product stability requirements.
Authenticity
What makes Neuramis wholesale different from other Korean fillers?
Neuramis uses high-purity HA raw materials and SHAPE purification, with residual BDDE reported as non-detectable below 0.4 ppm. Its monophasic structure provides high cohesivity and predictable tissue integration.
How does Yaksu Medi support authenticity checks?
We review factory-sealed packaging, visible lot information, and expiry details before preparing Neuramis for B2B export. Buyers can also verify product originality on arrival by checking the holographic seal and lot number consistency between the outer carton and syringe label.
Variants
Which Neuramis variant is most requested by clinics?
Neuramis Deep Lidocaine is often the most requested variant because it covers recurring demand for nasolabial folds, marionette lines, and lip volumization while providing integrated procedural comfort.
Can a clinic build one order across the full Neuramis portfolio?
Yes. Neuramis Light Lidocaine, Lidocaine, Deep, Deep Lidocaine, and Volume Lidocaine can be planned as one portfolio order so the clinic covers superficial, mid-dermal, deep, and volumizing protocols.
Clinical Overview
How long does Neuramis Deep or Volume last in tissue?
Standard longevity ranges from 6 to 12 months. Clinical references for Neuramis Volume Lidocaine include long-term responder data in Asian populations, with performance depending on injection site, patient metabolism, and technique.
Is lidocaine used only for procedural comfort?
Lidocaine primarily improves procedural comfort, but published product materials also discuss early inflammatory environment benefits. Lidocaine-free Neuramis Deep remains available for patients with amide-type anesthetic sensitivities.